Patni Nassar, Fatima Mahejabeen, Lamis Aselah, Siddiqui Shiza W, Ashok Tejaswini, Muhammad Ahmad
Internal Medicine, Deccan College of Medical Sciences, Hyderabad, IND.
Research, Dubai Medical College, Dubai, ARE.
Cureus. 2022 Jun 10;14(6):e25839. doi: 10.7759/cureus.25839. eCollection 2022 Jun.
Hypertension (HTN) is a complex multifactorial disease that is one of the most prevalent disorders in our modern world. It can lead to fatal complications like coronary artery disease (CAD) and congestive heart failure (CHF) in high-risk individuals. The silent nature of HTN also contributes to its immense caseload and, today, with a number of combinations and various antihypertensive agents, patient compliance is becoming increasingly difficult. This article has reviewed the role and mechanisms of magnesium (Mg) in reducing HTN in the human body so as to provide more information that may help include it as a mainstream antihypertensive regimen. This review has also shed light on the cardioprotective nature of Mg against pathologies like CHF with special mention to patient groups who are at high risk for low Mg levels. Many studies included in this article solidify the former link, but some also provide contradicting data.
高血压（HTN）是一种复杂的多因素疾病，是现代社会中最普遍的疾病之一。在高危个体中，它可导致致命并发症，如冠状动脉疾病（CAD）和充血性心力衰竭（CHF）。高血压的隐匿性也导致了其庞大的病例数，如今，由于有多种联合用药和各类抗高血压药物，患者的依从性正变得越来越困难。本文综述了镁（Mg）在降低人体高血压方面的作用和机制，以便提供更多信息，可能有助于将其纳入主流抗高血压治疗方案。本综述还揭示了镁对CHF等病症的心脏保护作用，特别提到了镁水平低风险高的患者群体。本文纳入的许多研究证实了前者的联系，但也有一些提供了相互矛盾的数据。
