Zickert I, Emilson C G, Krasse B
Infect Immun. 1983 Feb;39(2):982-5. doi: 10.1128/iai.39.2.982-985.1983.
The caries incidence at various levels of Streptococcus mutans infection was analyzed in a control group and a test group. In the control group, the incidence of caries and the duration of S. mutans infection were significantly correlated. In the test group, the S. mutans infection was suppressed by antimicrobial measures when the number of S. mutans exceeded 250 X 10(3) CFU per ml of saliva. The results illustrate that the level and duration of the S. mutans infection are strongly correlated to the incidence of caries. The findings support the concept of S. mutans as a key cariogenic microorganism and illustrate the value of antimicrobial treatment in the prevention of caries.
在一个对照组和一个试验组中分析了不同变形链球菌感染水平下的龋齿发病率。在对照组中，龋齿发病率与变形链球菌感染持续时间显著相关。在试验组中，当每毫升唾液中变形链球菌数量超过250×10³CFU时，通过抗菌措施抑制了变形链球菌感染。结果表明，变形链球菌感染的水平和持续时间与龋齿发病率密切相关。这些发现支持了变形链球菌作为关键致龋微生物的概念，并说明了抗菌治疗在预防龋齿中的价值。
