Brown C, Sutton J V, Adler A, Feinroth M V, Feinroth M, Friedman E A, Berlyne G M
Nephron. 1983;33(1):17-20. doi: 10.1159/000182897.
The effect of water immersion to the neck on renal calcium and magnesium handling was studied in 11 nephrotic patients. There was an increase in the urinary excretion of both calcium and magnesium on immersion, and a return towards preimmersion control values in the hour following immersion. Clearances of calcium and magnesium, and fractional excretion of calcium and of magnesium all increased significantly during water immersion, and decreased in the postimmersion hour. However, magnesium excretion was 10-50 times greater than calcium excretion. Fractional excretion of sodium was highly significantly related to fractional excretion of calcium (p less than 0.001) and magnesium (p less than 0.001). The relationship between fractional excretion of phosphate and fractional excretion of calcium was statistically significant (p less than 0.05), as was that between fractional excretion of phosphate and that of magnesium (p less than 0.01). Magnesium and calcium fractional excretions were significantly correlated (p less than 0.01). It was concluded that the increase in calcium and magnesium excretion on immersion is likely to be related to the sodium diuresis caused by central hypervolemia due to immersion.
对11名肾病患者研究了颈部水浸对肾脏钙和镁处理的影响。浸水时钙和镁的尿排泄量均增加，浸水后1小时又恢复到浸水前的对照值。浸水期间钙和镁的清除率以及钙和镁的分数排泄均显著增加，浸水后1小时则降低。然而，镁排泄量比钙排泄量大10至50倍。钠的分数排泄与钙的分数排泄（p<0.001）和镁的分数排泄（p<0.001）高度显著相关。磷酸盐的分数排泄与钙的分数排泄之间的关系具有统计学意义（p<0.05），磷酸盐的分数排泄与镁的分数排泄之间的关系也是如此（p<0.01）。镁和钙的分数排泄显著相关（p<0.01）。得出的结论是，浸水时钙和镁排泄增加可能与浸水导致的中枢血容量过多引起的钠利尿有关。
