Hsiao S, Spencer R
Behav Neurosci. 1983 Apr;97(2):234-45. doi: 10.1037//0735-7044.97.2.234.
A detailed analysis of the licking response of rats to milk was made. The effects of cholecystokinin (CCK) and bombesin (BBS) on the consummatory response were compared. The normal licking response pattern was found not to change as the meal progressed; no predictor was found to indicate when the meal would terminate. Licks normally occurred at about six per second, but there were a few licks that occurred at about three per second, with no licking occurring in the intermediate range; thus a distinctive bimodal frequency distribution of the interlick interval was formed. Cholecystokinin was found to reduce the intake of milk and the related licking indexes as expected, but it also induced an unusual licking pattern: The contact duration was shortened, the interlick interval was lengthened, and there was an increase in the proportion of licks with long interlick intervals, the effects that accentuated the bimodality of the distribution of interlick intervals. Bombesin reduced the intake and the related licking indexes as expected; however, it did not induce any unusual licking characteristics as seen with CCK at comparable effective doses. The CCK effect may be mediated partially by a change in the motor aspect of the consummatory response; however, BBS reduced intake by simply decreasing the number of licks and shortening the intake duration.
对大鼠对牛奶的舔舐反应进行了详细分析。比较了胆囊收缩素（CCK）和蛙皮素（BBS）对进食反应的影响。发现正常的舔舐反应模式不会随着进食过程而改变；未发现有预测指标可表明进食何时会结束。舔舐通常以每秒约6次的频率发生，但也有一些舔舐以每秒约3次的频率发生，中间频率范围没有舔舐发生；因此形成了舔舐间隔的独特双峰频率分布。如预期的那样，发现胆囊收缩素会减少牛奶摄入量和相关的舔舐指标，但它也会诱导出一种不寻常的舔舐模式：接触持续时间缩短，舔舐间隔延长，舔舐间隔长的舔舐比例增加，这些效应加剧了舔舐间隔分布的双峰性。蛙皮素如预期的那样减少了摄入量和相关的舔舐指标；然而，在相当的有效剂量下，它并未像胆囊收缩素那样诱导出任何不寻常的舔舐特征。胆囊收缩素的作用可能部分是由进食反应的运动方面的变化介导的；然而，蛙皮素只是通过减少舔舐次数和缩短进食持续时间来减少摄入量。
