Cole G W, Headley J, Skowsky R
Diabetes Care. 1983 Mar-Apr;6(2):189-92. doi: 10.2337/diacare.6.2.189.
Scleredema diabeticorum is characterized by a dramatic increase in the thickness of the skin of the posterior neck and upper back. Of the 17 scleredema patients diagnosed by us in the last 15 yr, 16 have had type II diabetes mellitus. In a prospective study of 484 diabetic outpatients we found the prevalence of scleredema to be 2.5%. Angina pectoris was the only complication that occurred significantly more frequently in scleredematous diabetic patients than in a control group of diabetic patients without scleredema. Scleredema diabeticorum is a distinct cutaneous condition peculiar to diabetic individuals and ought not to be confused with scleredema of Buschke or scleroderma.
糖尿病性硬皮病的特征是后颈部和上背部皮肤厚度急剧增加。在过去15年中我们诊断的17例硬皮病患者中，16例患有II型糖尿病。在一项对484例糖尿病门诊患者的前瞻性研究中，我们发现硬皮病的患病率为2.5%。心绞痛是唯一在患有硬皮病的糖尿病患者中比无硬皮病的糖尿病对照组显著更频繁发生的并发症。糖尿病性硬皮病是糖尿病个体特有的一种独特的皮肤病症，不应与布希克硬皮病或硬皮病相混淆。
