Patel Divya R, Vora Neel, Chaudhary Rajvi, Sharma Vishnu, Dadhaniya Nikunj V
Internal Medicine, B.J. Medical College, Ahmedabad, IND.
Rheumatology, Apollo Hospitals, Ahmedabad, IND.
Cureus. 2023 Apr 29;15(4):e38300. doi: 10.7759/cureus.38300. eCollection 2023 Apr.
Scleredema adultorum of Buschke is a rare condition that presents as a scleroderma mimic and portends a diagnostic challenge to the clinician. It may be associated with monoclonal gammopathy, upper respiratory tract infection, or type II diabetes mellitus. In addition, it is associated with dermal collagen and aminoglycan deposits that cause the skin to thicken and stiffen. Typically, thickening and tightening begin in the neck and progress to the upper body, including the face, scalp, shoulders, and trunk, but sparing the palms and soles. Patients with minor skin involvement may not suffer any symptoms, whereas those with significant skin disease may develop stiffness and functional impairment. There are rare reports linking scleredema adultorum of Buschke with several infections such as human immunodeficiency virus infection, acquired immunodeficiency syndrome-related lipodystrophy syndrome, and streptococcal infection of the upper respiratory tract. Here, we present a case of scleredema adultorum of Buschke associated with hepatitis B infection.
布希克成人硬肿病是一种罕见疾病，表现为硬皮病样症状，给临床医生带来诊断挑战。它可能与单克隆丙种球蛋白病、上呼吸道感染或II型糖尿病有关。此外，它与导致皮肤增厚和变硬的真皮胶原蛋白和氨基聚糖沉积有关。通常，增厚和紧绷始于颈部，然后发展到上半身，包括面部、头皮、肩部和躯干，但手掌和脚底除外。皮肤受累较轻的患者可能没有任何症状，而患有严重皮肤病的患者可能会出现僵硬和功能障碍。有罕见报道将布希克成人硬肿病与几种感染联系起来，如人类免疫缺陷病毒感染、获得性免疫缺陷综合征相关脂肪营养不良综合征和上呼吸道链球菌感染。在此，我们报告一例与乙型肝炎感染相关的布希克成人硬肿病病例。
