年龄、性别和饮食对婴儿艰难梭菌无症状定植的影响。
Influence of age, sex, and diet on asymptomatic colonization of infants with Clostridium difficile.
作者信息
Cooperstock M, Riegle L, Woodruff C W, Onderdonk A
出版信息
J Clin Microbiol. 1983 May;17(5):830-3. doi: 10.1128/jcm.17.5.830-833.1983.
Abstract
A total of 40% of 107 stool samples from infants 1 to 52 weeks of age were found to contain Clostridium difficile antigens, detected by counterimmunoelectrophoresis. Within the group tested, there was no detectable variation by age or sex. Infants fed formula were nearly four times more likely to carry C. difficile than were those exclusively breast fed (62 versus 16%), whereas breast-fed infants also receiving formula or solids had an intermediate rate of colonization (35%). The distributions were similar when a subgroup with the highest levels of antigen was assessed separately. These data will be useful in considering potential pathogenic activities of C. difficile colonization in infancy.
摘要
通过对流免疫电泳检测发现，107份1至52周龄婴儿的粪便样本中，共有40%含有艰难梭菌抗原。在测试组中，未发现按年龄或性别划分的可检测差异。用配方奶喂养的婴儿携带艰难梭菌的可能性几乎是纯母乳喂养婴儿的四倍（62%对16%），而同时接受配方奶或固体食物喂养的母乳喂养婴儿的定植率处于中间水平（35%）。当单独评估抗原水平最高的亚组时，分布情况相似。这些数据将有助于考虑婴儿期艰难梭菌定植的潜在致病活性。
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