患病新生儿的血浆17-羟孕酮浓度
Plasma 17-hydroxyprogesterone concentrations in ill newborn infants.
作者信息
Murphy J F, Joyce B G, Dyas J, Hughes I A
出版信息
Arch Dis Child. 1983 Jul;58(7):532-4. doi: 10.1136/adc.58.7.532.
Abstract
Plasma 17-hydroxyprogesterone concentrations were determined in 47 preterm and term infants who were ill from a variety of causes. The results were compared with those in 53 healthy term infants. Mean plasma 17-hydroxyprogesterone values were appreciably higher in ill term and healthy preterm infants compared with healthy term infants, but the highest values were found in ill preterm infants. None of the infants had adrenal disease but some very ill infants had plasma 17-hydroxyprogesterone values approaching those seen in untreated infants with congenital adrenal hyperplasia. Interpretation of the results of plasma steroid measurements in newborn infants must take account of gestational age and the presence of stress related illness.
摘要
对47名因各种病因患病的早产和足月婴儿测定了血浆17-羟孕酮浓度。将结果与53名健康足月婴儿的结果进行了比较。与健康足月婴儿相比，患病足月婴儿和健康早产婴儿的平均血浆17-羟孕酮值明显更高，但最高值出现在患病早产婴儿中。所有婴儿均无肾上腺疾病，但一些重病婴儿的血浆17-羟孕酮值接近未经治疗的先天性肾上腺皮质增生婴儿的值。对新生儿血浆类固醇测量结果的解释必须考虑胎龄和应激相关疾病的存在。
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本文引用的文献
1
Plasma levels of aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, cortisol, and cortisone during infancy and childhood.婴儿期和儿童期血浆中醛固酮、皮质酮、11-脱氧皮质酮、孕酮、17-羟孕酮、皮质醇和可的松的水平。
Pediatr Res. 1980 Jan;14(1):39-46. doi: 10.1203/00006450-198001000-00010.
2
Pseudohypoaldosteronism. Response to long-term treatment with indomethacin.假性醛固酮增多症。对吲哚美辛长期治疗的反应。
Arch Dis Child. 1982 Sep;57(9):718-20. doi: 10.1136/adc.57.9.718.
3
A pilot newborn screening for congenital adrenal hyperplasia in Alaska.阿拉斯加先天性肾上腺皮质增生症新生儿筛查试点项目。
J Clin Endocrinol Metab. 1982 Sep;55(3):413-20. doi: 10.1210/jcem-55-3-413.
4
Renal function in the newborn infant.新生儿的肾功能
Pediatr Clin North Am. 1982 Aug;29(4):777-90. doi: 10.1016/s0031-3955(16)34211-0.
5
Diagnosis of congenital adrenal hyperplasia by measurement of plasma 17-hydroxyprogesterone.通过检测血浆17-羟孕酮诊断先天性肾上腺皮质增生症。
Arch Dis Child. 1972 Feb;47(251):62-5. doi: 10.1136/adc.47.251.62.
6
Microfilter paper method for 17 alpha-hydroxyprogesterone radioimmunoassay: its application for rapid screening for congenital adrenal hyperplasia.
J Clin Endocrinol Metab. 1977 Nov;45(5):1003-8. doi: 10.1210/jcem-45-5-1003.
7
Ontogenic study of plasma 17alpha-hydroxyprogesterone in the human. I. Postnatal period: evidence for a transient ovarian activity in infancy.
Pediatr Res. 1978 Jan;12(1):6-11. doi: 10.1203/00006450-197801000-00003.
8
Internal quality control of radioimmunoassays.
J Endocrinol. 1978 Feb;76(2):203-10. doi: 10.1677/joe.0.0760203.
9
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10
A method for identification and follow-up of patients with a steroid-21-hydroxylase deficiency.一种用于识别和随访类固醇21-羟化酶缺乏症患者的方法。
Clin Chim Acta. 1979 Mar 1;92(2):117-24. doi: 10.1016/0009-8981(79)90104-9.
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