Purola E E, Halila H, Vesterinen E
Gynecol Oncol. 1983 Aug;16(1):34-40. doi: 10.1016/0090-8258(83)90006-9.
One hundred and three adolescent women with cervical cytology suggestive of mild to moderate dysplasia were studied for the presence of condylomatous lesion. The analysis of smears revealed cells suggestive of condyloma in 81% of the cases. In histopathologic studies cervical lesions typical of condyloma were observed in 59 preparations. Of these 16 were papillary and 35 were flat condylomas, and in 8 cervices both papillary and flat condylomatous lesions were present. Colposcopic examination showed an atypical transformation zone in 57 cases. Papillary condylomas were present in 24 cervices in 7 cases combined with an atypical transformation zone. In addition to the cervical epithelial atypias there were 18 cases in which colposcopic and histologic examination of vagina revealed papillary warts, 13 of them combined with cervical condylomas. In four patients vaginal leucoplakia was seen and all were histologically flat condylomas. Thus, in 68 cases or in 66% of adolescent women having abnormal cervical cytology, histological investigation revealed condylomatous changes.
对103名宫颈细胞学检查提示轻度至中度发育异常的青春期女性进行了尖锐湿疣病变检查。涂片分析显示，81%的病例中发现了提示尖锐湿疣的细胞。组织病理学研究中，在59份标本中观察到了典型的宫颈尖锐湿疣病变。其中16例为乳头状尖锐湿疣，35例为扁平状尖锐湿疣，8例宫颈同时存在乳头状和扁平状尖锐湿疣病变。阴道镜检查显示57例有非典型转化区。7例中24个宫颈存在乳头状尖锐湿疣，同时伴有非典型转化区。除宫颈上皮发育异常外，18例阴道镜及组织学检查发现阴道有乳头状疣，其中13例合并宫颈尖锐湿疣。4例患者可见阴道白斑，组织学检查均为扁平状尖锐湿疣。因此，在68例（占宫颈细胞学异常青春期女性的66%）中，组织学检查发现了尖锐湿疣样改变。
