Syrjänen K J
Arch Gynecol. 1979 Aug;227(2):153-61. doi: 10.1007/BF02103290.
One hundred eighty-four women with a histologically verified dysplastic or neoplastic lesion in the uterine cervical epithelium were histologically assessed with special reference to the presence of the various histological types of condyloma in these epithelial specimens. Histological changes fulfilling the previously outlined criteria of the flat, inverted, and papillomatous condylomas were encountered in 91 (49.4%) women. Condylomatous lesions were seen in association with all degrees of epithelial atypia from mild dysplasia to frankly invasive cervical carcinoma, which seemed to develop at significantly earlier age when concomitant condylomatous lesion was present than with its absence (p less than 0.001). The serious consideration of the relationship between the condylomatous lesions and the uterine cervical was emphasized.
对184例经组织学证实子宫颈上皮有发育异常或肿瘤性病变的女性进行了组织学评估,特别关注这些上皮标本中各种组织学类型尖锐湿疣的存在情况。91例(49.4%)女性出现了符合先前概述的扁平、内翻和乳头状尖锐湿疣标准的组织学变化。尖锐湿疣病变与从轻度发育异常到明显浸润性宫颈癌的所有程度的上皮异型性相关,当伴有尖锐湿疣病变时,浸润性宫颈癌似乎比无病变时在明显更早的年龄发生(p<0.001)。强调了对尖锐湿疣病变与子宫颈之间关系的认真考虑。