比利时心脏病预防项目：自我报告的吸烟行为与血清硫氰酸盐浓度的比较
Belgian heart disease prevention project: comparison of self-reported smoking behaviour with serum thiocyanate concentrations.
作者信息
Kornitzer M, Vanhemeldonck A, Bourdoux P, de Backer G
出版信息
J Epidemiol Community Health. 1983 Jun;37(2):132-6. doi: 10.1136/jech.37.2.132.
Abstract
At the end of a multifactorial cardiovascular preventive trial serum thiocyanate was measured in random samples of 1035 cases and 1087 controls. A cut-off point 0.45 mg/dl (77.6/mumol/l) gave a sensitivity of 82.1% among the cigarette smokers in the control group and a specificity of 91.0% among the non-smokers. When the intervention and control groups are compared in terms of self-reported smoking behaviour non-significant differences in mean thiocyanate concentration are observed for those who never smoked, ex-cigarette smokers, actual cigarette smokers, and in four different cigarette smoking categories. Our results fail to confirm the reported pessimistic views concerning the validity of self-reported smoking behaviour in subjects taking part in intervention trials.
摘要
在一项多因素心血管预防试验结束时，对1035例病例和1087例对照的随机样本进行了血清硫氰酸盐检测。截断点为0.45mg/dl（77.6/μmol/l）时，对照组中吸烟者的敏感性为82.1%，非吸烟者的特异性为91.0%。当根据自我报告的吸烟行为对干预组和对照组进行比较时，对于从不吸烟、曾经吸烟、当前吸烟的人群以及四个不同吸烟类别，硫氰酸盐平均浓度均未观察到显著差异。我们的结果未能证实有关参与干预试验的受试者自我报告吸烟行为有效性的悲观观点。
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