用L-3-123I-碘-α-甲基酪氨酸对实验性无色素性眼黑色素瘤进行非接触检测。
Noncontact detection of experimental amelanotic ocular melanoma with L-3-123I-iodo-alpha-methyltyrosine.
作者信息
Bockslaff H, Spitznas M, Hahn I, Kloster G
出版信息
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1981;217(4):255-66. doi: 10.1007/BF00429286.
PMID:6915722
Abstract
An application of L-3-123I-iodo-alpha-methyltyrosine for the detection of ocular melanoma is presented. In rabbits with malignant Greene amelanotic melanoma transplanted to the anterior chamber of the eye, all tumors were detected in positive contrast using a gamma camera with a single pinhole collimator. The smallest tumor identified weighed 65 mg. Our data are compared with those obtained with 32PO4, 67Ga, 203Pb or labelled iodochloroquine.
摘要
介绍了L-3-123I-碘-α-甲基酪氨酸在检测眼黑色素瘤中的应用。在将恶性格林无色素性黑色素瘤移植到眼前房的兔子中，使用带有单针孔准直器的γ相机以阳性对比检测到所有肿瘤。鉴定出的最小肿瘤重65毫克。我们的数据与用32PO4、67Ga、203Pb或标记的碘氯喹啉获得的数据进行了比较。
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