• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

作者信息

Tischler M E, Desautels M, Goldberg A L

出版信息

J Biol Chem. 1982 Feb 25;257(4):1613-21.

PMID:6915936
Abstract
摘要

相似文献

1
Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?亮氨酸、亮氨酰 - tRNA 或亮氨酸的某些代谢产物是否调节骨骼肌和心肌中的蛋白质合成与降解？
J Biol Chem. 1982 Feb 25;257(4):1613-21.
2
Equilibration of leucine between the plasma compartment and leucyl-tRNA in the heart, and turnover of cardiac myosin heavy chain.血浆区室与心脏中亮氨酰 - tRNA之间亮氨酸的平衡，以及心肌肌球蛋白重链的周转。
Biochem J. 1981 Jan 15;194(1):365-8. doi: 10.1042/bj1940365.
3
Precursor pools of protein synthesis: a stable isotope study in a swine model.蛋白质合成的前体池：猪模型中的稳定同位素研究
Am J Physiol. 1994 Aug;267(2 Pt 1):E203-9. doi: 10.1152/ajpendo.1994.267.2.E203.
4
Protein synthesis in pulmonary alveolar macrophages. Source of amino acids for leucyl-tRNA.肺泡巨噬细胞中的蛋白质合成。亮氨酰 - tRNA的氨基酸来源。
Biochim Biophys Acta. 1981 Mar 26;653(1):108-17. doi: 10.1016/0005-2787(81)90109-x.
5
Analysis of early responses to growth hormone on amino acid transport and protein synthesis in diaphragms of young normal rats.幼年正常大鼠膈肌中生长激素对氨基酸转运和蛋白质合成早期反应的分析
Endocrinology. 1980 Jan;106(1):291-7. doi: 10.1210/endo-106-1-291.
6
Regulation by insulin of protein and amino acid metabolism.胰岛素对蛋白质和氨基酸代谢的调节。
Sci Basis Med Annu Rev. 1971:178-91.
7
Isolation of aminoacyl-tRNA and its labeling with stable-isotope tracers: Use in studies of human tissue protein synthesis.氨酰基-tRNA的分离及其用稳定同位素示踪剂标记：用于人体组织蛋白质合成的研究。
Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5892-6. doi: 10.1073/pnas.88.13.5892.
8
Protein synthesis in rat lung. Measurements in vivo based on leucyl-tRNA and rapidly turning-over procollagen I.大鼠肺中的蛋白质合成。基于亮氨酰 - tRNA和快速周转的原胶原蛋白I的体内测量。
Biochem J. 1984 Aug 15;222(1):77-83. doi: 10.1042/bj2220077.
9
[Biological activity of tRNA in rat liver during cycloheximide-blocked translation].[环己酰亚胺阻断翻译过程中大鼠肝脏tRNA的生物学活性]
Ukr Biokhim Zh (1978). 1982 Mar-Apr;54(2):204-7.
10
Aminoacyl transfer from phenylalanyl-tRNA microinjected into Xenopus laevis oocytes.从微注射到非洲爪蟾卵母细胞中的苯丙氨酰 - tRNA进行氨酰基转移。
Biochem Biophys Res Commun. 1977 Nov 21;79(2):352-6. doi: 10.1016/0006-291x(77)90164-4.

引用本文的文献

1
Prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in the intensive care unit.前瞻性随机、安慰剂对照研究：支链氨基酸输注作为重症监护病房肝手术后患者辅助治疗的作用。
BMC Gastroenterol. 2025 Jun 19;25(1):439. doi: 10.1186/s12876-025-03696-3.
2
-hydroxy--methylbutyrate Attenuates Age-Dependent Loss of Flight Ability and Extends Lifespan in Drosophila.β-羟基-β-甲基丁酸可减轻果蝇中与年龄相关的飞行能力丧失并延长其寿命。
Int J Mol Sci. 2025 Mar 15;26(6):2664. doi: 10.3390/ijms26062664.
3
Long-term leucine supplementation increases body weight in goats by controlling appetite and muscle protein synthesis under protein-restricted conditions.
在蛋白质限制条件下，长期补充亮氨酸可通过控制山羊食欲和肌肉蛋白质合成来增加体重。
Anim Nutr. 2024 Nov 29;20:404-418. doi: 10.1016/j.aninu.2024.09.005. eCollection 2025 Mar.
4
Muscle Amino Acid and Adenine Nucleotide Metabolism during Exercise and in Liver Cirrhosis: Speculations on How to Reduce the Harmful Effects of Ammonia.运动及肝硬化过程中的肌肉氨基酸和腺嘌呤核苷酸代谢：关于如何降低氨的有害影响的思考
Metabolites. 2022 Oct 13;12(10):971. doi: 10.3390/metabo12100971.
5
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells.支链氨基酸调节猪乳腺上皮细胞内的蛋白质周转。
Amino Acids. 2022 Nov;54(11):1491-1504. doi: 10.1007/s00726-022-03203-y. Epub 2022 Sep 9.
6
Beneficial Effects of Resveratrol in Mouse Gastrocnemius: A Hint to Muscle Phenotype and Proteolysis.白藜芦醇对小鼠比目鱼肌的有益作用：肌肉表型和蛋白水解的提示。
Cells. 2021 Sep 15;10(9):2436. doi: 10.3390/cells10092436.
7
α-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFα/IFNγ Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube.α-羟基异己酸通过抑制 iNOS 和 IL-6 减少 TNFα/IFNγ 共暴露诱导的蛋白降解和肌管萎缩，从而降低蛋白质合成。
Nutrients. 2021 Jul 13;13(7):2391. doi: 10.3390/nu13072391.
8
Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism.支链氨基酸：骨骼肌中的分解代谢及其对肌肉和全身代谢的影响
Front Physiol. 2021 Jul 20;12:702826. doi: 10.3389/fphys.2021.702826. eCollection 2021.
9
Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity.韩国成年人饮食中支链氨基酸摄入量与骨骼肌质量指数之间的关联：与肥胖的相互作用。
Nutr Res Pract. 2021 Apr;15(2):203-212. doi: 10.4162/nrp.2021.15.2.203. Epub 2020 Nov 30.
10
Branched-Chain Amino Acids and Branched-Chain Keto Acids in Hyperammonemic States: Metabolism and as Supplements.高氨血症状态下的支链氨基酸和支链酮酸：代谢与作为补充剂的情况
Metabolites. 2020 Aug 9;10(8):324. doi: 10.3390/metabo10080324.