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原子弹的健康益处。

Atomic bomb health benefits.

机构信息

Lawrence, KS, USA.

出版信息

Dose Response. 2008;6(4):369-82. doi: 10.2203/dose-response.08-009.Luckey. Epub 2008 Aug 11.

DOI:10.2203/dose-response.08-009.Luckey
PMID:19088902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2592990/
Abstract

Media reports of deaths and devastation produced by atomic bombs convinced people around the world that all ionizing radiation is harmful. This concentrated attention on fear of miniscule doses of radiation. Soon the linear no threshold (LNT) paradigm was converted into laws. Scientifically valid information about the health benefits from low dose irradiation was ignored. Here are studies which show increased health in Japanese survivors of atomic bombs. Parameters include decreased mutation, leukemia and solid tissue cancer mortality rates, and increased average lifespan. Each study exhibits a threshold that repudiates the LNT dogma. The average threshold for acute exposures to atomic bombs is about 100 cSv. Conclusions from these studies of atomic bomb survivors are: One burst of low dose irradiation elicits a lifetime of improved health.Improved health from low dose irradiation negates the LNT paradigm.Effective triage should include radiation hormesis for survivor treatment.

摘要

媒体对原子弹造成的死亡和破坏的报道使全世界的人相信,所有电离辐射都是有害的。这使得人们对微小剂量辐射的恐惧集中起来。很快,线性无阈值(LNT)范式就被转化为法律。关于低剂量照射带来健康益处的科学有效信息被忽视了。这里有一些研究表明,原子弹的日本幸存者的健康状况有所改善。参数包括降低突变、白血病和实体组织癌症死亡率,以及增加平均寿命。每一项研究都显示出一个拒绝 LNT 教条的阈值。急性暴露于原子弹的平均阈值约为 100 毫希沃特。这些原子弹幸存者研究的结论是:

  1. 一次低剂量照射会产生一生的健康改善。

  2. 低剂量照射带来的健康改善否定了 LNT 范式。

  3. 有效的分诊应包括对幸存者的辐射兴奋治疗。

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本文引用的文献

1
Nurture with ionizing radiation: a provocative hypothesis.用电离辐射培育:一个引人深思的假说。
Nutr Cancer. 1999;34(1):1-11. doi: 10.1207/S15327914NC340101.
2
Estimating cancer risks from low doses of ionizing radiation.低剂量电离辐射致癌风险评估
Science. 1980 Sep 12;209(4462):1197-203. doi: 10.1126/science.7403879.
3
Genetic effects of the atomic bombs: a reappraisal.原子弹的遗传效应:重新评估
Science. 1981 Sep 11;213(4513):1220-7. doi: 10.1126/science.7268429.
4
Search for mutations affecting protein structure in children of atomic bomb survivors: preliminary report.探寻原子弹爆炸幸存者子女中影响蛋白质结构的突变:初步报告。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4221-5. doi: 10.1073/pnas.77.7.4221.
5
Dose-response analyses among atomic bomb survivors exposed to low-level radiation.遭受低剂量辐射的原子弹幸存者的剂量反应分析。
Health Phys. 1987 May;52(5):645-52. doi: 10.1097/00004032-198705000-00017.
6
The children of parents exposed to atomic bombs: estimates of the genetic doubling dose of radiation for humans.遭受原子弹辐射的父母所生子女:人类辐射遗传加倍剂量的估计
Am J Hum Genet. 1990 Jun;46(6):1053-72.
7
Studies of the mortality of A-bomb survivors. 9. Mortality, 1950-1985: Part 2. Cancer mortality based on the recently revised doses (DS86).原子弹爆炸幸存者死亡率研究。9. 死亡率,1950 - 1985年:第2部分。基于最新修订剂量(DS86)的癌症死亡率。
Radiat Res. 1990 Feb;121(2):120-41.
8
Apparently beneficial effect of low to intermediate doses of A-bomb radiation on human lifespan.低至中等剂量原子弹辐射对人类寿命的明显有益影响。
Int J Radiat Biol. 1990 Dec;58(6):1035-43. doi: 10.1080/09553009014552341.
9
Studies of the mortality of A-bomb survivors. 9. Mortality, 1950-1985: Part 3. Noncancer mortality based on the revised doses (DS86).原子弹爆炸幸存者死亡率研究。9. 死亡率,1950 - 1985年:第3部分。基于修订剂量(DS86)的非癌症死亡率。
Radiat Res. 1992 May;130(2):249-66.