Schneider V, Barnes L A
Acta Cytol. 1981 Nov-Dec;25(6):616-22.
The histologic and cytologic manifestation of cervical decidual reaction in pregnancy was investigated. Histologically, cervical decidua was found in 30.8% of 191 uteri removed during pregnancy. Characteristic features were focal occurrence, subepithelial location and frequent disruption of the overlying epithelium. Cytologically, decidual cells were found in 34% of patients with histologically confirmed cervical decidual reaction. The number of decidual cells per smear ranged from 11 to 208, with a mean of 105. The majority of cells occurred in aggregates and stained basophilic or amphophilic. Outstanding diagnostic features of decidual cells in smears were finely granular chromatin pattern in 96%, prominent nucleoli in over 80% and marked nuclear enlargement. Cytometrically, decidual cells showed a wide variation in size. The nuclear area ranged from 31 sq micrometers to 320 sq micrometers, with a mean of 111 sq micrometers. In the differential diagnosis, tissue repair, dysplasia, carcinoma in situ and endocervical adenocarcinoma must be considered.
对妊娠期宫颈蜕膜反应的组织学和细胞学表现进行了研究。组织学上，在191例孕期切除的子宫中，30.8%发现有宫颈蜕膜。其特征为局灶性出现、上皮下定位以及上皮经常中断。细胞学上，在组织学确诊为宫颈蜕膜反应的患者中，34%发现有蜕膜细胞。每张涂片的蜕膜细胞数量为11至208个，平均为105个。大多数细胞聚集成团，染成嗜碱性或嗜双色性。涂片中蜕膜细胞的突出诊断特征为96%有细颗粒状染色质模式，80%以上有明显核仁，且核显著增大。细胞测量显示，蜕膜细胞大小差异很大。核面积为31平方微米至320平方微米，平均为111平方微米。在鉴别诊断中，必须考虑组织修复、发育异常、原位癌和宫颈腺癌。
