小家鼠不同亚种主要组织相容性复合体分子的生化比较：等位基因跨物种进化的证据。
Biochemical comparison of major histocompatibility complex molecules from different subspecies of Mus musculus: evidence for trans-specific evolution of alleles.
作者信息
Arden B, Klein J
出版信息
Proc Natl Acad Sci U S A. 1982 Apr;79(7):2342-6. doi: 10.1073/pnas.79.7.2342.
Abstract
H-2 haplotypes were extracted from wild mice of three subspecies, Mus musculus domesticus, M. m. molossinus, and M. m. castaneus, that are known to have been separated from one another for some 1 to 2 million years. Serologically indistinguishable molecules controlled by some of the polymorphic H-2 loci were compared by tryptic peptide mapping, and the maps were found to be identical. In addition, a number of instances of biochemically indistinguishable H-2 molecules were found among wild mice and inbred strains of the M. m. domesticus subspecies. These findings suggest that some of the H-2 alleles have not altered for greater than 1 million years. To reconcile this apparent stability of H-2 genes with their extraordinary polymorphism (some 100 alleles at each of the polymorphic H-2 loci), it is proposed that the H-2 alleles evolve as if they were separate loci.
摘要
从三个亚种的野生小鼠中提取了H-2单倍型，这三个亚种分别是小家鼠（Mus musculus domesticus）、日本小家鼠（M. m. molossinus）和栗色小家鼠（M. m. castaneus），已知它们彼此分离约100至200万年。通过胰蛋白酶肽图谱比较了一些多态性H-2位点控制的血清学上无法区分的分子，发现这些图谱是相同的。此外，在野生小鼠和小家鼠亚种的近交系中发现了许多生化上无法区分的H-2分子实例。这些发现表明，一些H-2等位基因在超过100万年的时间里没有发生改变。为了使H-2基因这种明显的稳定性与其非凡的多态性（每个多态性H-2位点约有100个等位基因）相协调，有人提出H-2等位基因的进化方式就好像它们是独立的位点。
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本文引用的文献
1
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J Immunol. 1980 Dec;125(6):2424-8.
2
Genetic variation in small multigene families.小多基因家族中的遗传变异。
Genet Res. 1981 Apr;37(2):133-49. doi: 10.1017/s0016672300020115.
3
Polymorphism of the mouse H-2 loci.小鼠H-2基因座的多态性。
Immunol Rev. 1981;60:23-57. doi: 10.1111/j.1600-065x.1981.tb00361.x.
4
Primary structure of murine major histocompatibility complex alloantigens: amino acid sequence of the amino-terminal one hundred and seventy-three residues of the H-2Kb glycoprotein.小鼠主要组织相容性复合体同种异体抗原的一级结构：H-2Kb糖蛋白氨基末端173个残基的氨基酸序列。
Biochemistry. 1980 Jan 22;19(2):306-15. doi: 10.1021/bi00543a009.
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6
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7
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