基于基因组DNA限制性片段长度多态性的实验室来源和野生小家鼠品系之间的系统发育关系。

Phylogenetic relationships among laboratory and wild-origin Mus musculus strains on the basis of genomic DNA RFLPs.

作者信息

Santos J, Cole Y, Pellicer A

机构信息

Department of Pathology, New York University School of Medicine, New York 10016.

出版信息

Mamm Genome. 1993 Sep;4(9):485-92. doi: 10.1007/BF00364782.

DOI:10.1007/BF00364782

PMID:7906967

Abstract

Genetic distance measures between the laboratory mouse strains C57BL/6J and RF/J and the wild-origin Mus musculus mouse strains CAST/Ei, MOLF/Ei, POSCH I, and CZECH II were estimated by allelic patterns revealed by RFLP analysis. These results suggest phylogenetic relationships indicating that the mouse strains related to the subspecies M.m. domesticus (RF/J, POSCH I and C57BL/6J) are more closely related to the CAST/Ei strain (derived from M.m. castaneus) than to the strains CZECH II (M.m. musculus) and MOLF/Ei (M.m. molossinus). Furthermore, the hybrid strain C57BL/6J is more closely related to POSCH I (M.m. poschiavinus) than to RF/J as calculated by the method distance measures of Cavalli-Sforza and Edwards (Evolution 21,550, 1967), Nei's minimum (Am. Natural. 106,283, 1972) and unbiased minimum (Genetics 89,583, 1978), Edwards (Biometrics 27,873, 1971; Genetic Distance, p. 41, 1974) and Rogers modified (1986).

摘要

通过限制性片段长度多态性（RFLP）分析所揭示的等位基因模式，估算了实验室小鼠品系C57BL/6J和RF/J与野生来源的小家鼠品系CAST/Ei、MOLF/Ei、POSCH I和CZECH II之间的遗传距离。这些结果表明了系统发育关系，即与小家鼠亚种（RF/J、POSCH I和C57BL/6J）相关的小鼠品系与CAST/Ei品系（源自栗色小家鼠）的关系比与CZECH II品系（小家鼠）和MOLF/Ei品系（小家鼠）的关系更为密切。此外，按照卡瓦利 - 斯福尔扎和爱德华兹（《进化》21,550, 1967年）、内的最小值（《美国博物学家》106,283, 1972年）和无偏最小值（《遗传学》89,583, 1978年）、爱德华兹（《生物统计学》27,873, 1971年；《遗传距离》，第41页，1974年）以及罗杰斯修正法（1986年）所计算的距离度量方法，杂交品系C57BL/6J与POSCH I（波希米亚小家鼠）的关系比与RF/J的关系更为密切。