豚鼠胰腺中的阿片样多肽
Opioid polypeptides in guinea pig pancreas.
作者信息
Stern A S, Wurzburger R J, Barkey R, Spector S
出版信息
Proc Natl Acad Sci U S A. 1982 Nov;79(21):6703-6. doi: 10.1073/pnas.79.21.6703.
Abstract
Extracts from guinea pig pancreas were found to contain high molecular weight enkephalin-containing polypeptides as well as free [Met]enkephalin and [Leu]enkephalin and the hexa-, hepta-, and octapeptides derived from proenkephalin. Within the limits of sensitivity of our assay (10 fmol/g of tissue), beta-endorphin and beta-lipotropin were undetectable.
摘要
研究发现，豚鼠胰腺提取物中含有高分子量的含脑啡肽多肽，以及游离的[甲硫氨酸]脑啡肽和[亮氨酸]脑啡肽，还有源自前脑啡肽的六肽、七肽和八肽。在我们检测方法的灵敏度范围内（10飞摩尔/克组织），未检测到β-内啡肽和β-促脂素。
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