[Effect of anti-brain sera on the appearance of hypersensitivity of the delayed type and its adoptive transfer].

The effect of rabbit immunosera against CBA mouse brain on lymphoid cells of guinea pigs was studied in experiments with adoptive transfer of hypersensitivity of the delayed type. In vitro treatment of the transferred cells abolished their capacity for adoptive transfer. Such an effect of the sera was not selective with respect to the sensitizing antigen, i. e. it was nonspecific. Pretreatment with sera blocked the development of local allergic reactions of the delayed type and did not affect reactions of the immediate type.