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用于估计发展中国家脊髓灰质炎流行率和年发病率的临床调查技术。

Clinical survey techniques to estimate prevalence and annual incidence of poliomyelitis in developing countries.

作者信息

LaForce F M, Lichnevski M S, Keja J, Henderson R H

出版信息

Bull World Health Organ. 1980;58(4):609-20.

Abstract

Recent epidemiological data suggest that poliomyelitis is a more important public health problem in developing countries than was originally suspected. Because of the availability of a cheap, effective, but labile oral vaccine, it is important that countries determine the incidence of poliomyelitis in order to determine the necessity and speed with which a vaccination programme should be introduced.Sequelae of poliomyelitis are distinctive and can be used to study the incidence of residual paralysis in children above the age of 5 years. Prevalence data for lameness due to poliomyelitis can then be translated into rates of annual incidence of paralytic disease. Lameness surveys can be efficiently done in schools and data are reliable as long as a similar search for lame children is done amongst children of the same age group who do not attend school but are in the geographical area served by the school. House-to-house surveys, while more time-consuming, are more reliable.

摘要

近期的流行病学数据表明,脊髓灰质炎在发展中国家是一个比最初预想更为重要的公共卫生问题。由于有了一种廉价、有效但不稳定的口服疫苗,各国确定脊髓灰质炎的发病率以决定引入疫苗接种计划的必要性和速度就显得很重要。脊髓灰质炎的后遗症很独特,可用于研究5岁以上儿童的残留麻痹发病率。然后,脊髓灰质炎所致跛行的患病率数据可转化为麻痹性疾病的年发病率。在学校进行跛行调查效率很高,只要在同一地理区域内未上学但年龄相同的儿童中进行类似的跛足儿童筛查,数据就是可靠的。逐户调查虽然更耗时,但更可靠。

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