Nicholas D D, Kratzer J H, Ofosu-Amaah S, Belcher D W
Br Med J. 1977 Apr 16;1(6067):1009-12. doi: 10.1136/bmj.1.6067.1009.
Children were examined for lameness in the Danfa Project district of rural Ghana to assess the impact of endemic poliomyelitis and to test a widely held hypothesis that paralytic poliomyelitis is relatively rare in such districts (less than 1 per 1000 children affected). The observed prevalence of lameness attributable to poliomyelitis was 7 per 1000 school-aged children, and the annual incidence is estimated to be at least 28 per 100 000 population. Although no evidence for an epidemic was found, these rates are comparable with those in the USA and Europe during the years of severe epidemics and indicate that a high price is being paid in the Danfa district for the natural acquisition of immunity. As a result, immunisation against poliomyelitis has been given high priority. A teacher questionnaire was also tested for use in postal surveys as a rapid means of estimating the prevalence of lamenes attributable to poliomyelitis in countries with a reasonable network of primary schools.
在加纳农村的丹法项目区对儿童进行了跛足检查,以评估地方性脊髓灰质炎的影响,并检验一种广泛存在的假设,即在这些地区麻痹性脊髓灰质炎相对罕见(每1000名受影响儿童中不到1例)。观察到的因脊髓灰质炎导致的跛足患病率为每1000名学龄儿童中有7例,估计年发病率至少为每10万人中有28例。虽然未发现疫情证据,但这些比率与美国和欧洲在严重疫情年份的比率相当,表明丹法地区因自然获得免疫力而付出了高昂代价。因此,脊髓灰质炎免疫接种被列为高度优先事项。还对一份教师调查问卷进行了测试,以用于邮政调查,作为在拥有合理小学网络的国家快速估计因脊髓灰质炎导致的跛足患病率的一种手段。