Ofosu-Amaah S, Kratzer J H, Nicholas D D
Br Med J. 1977 Apr 16;1(6067):1012-4. doi: 10.1136/bmj.1.6067.1012.
A postal survey of lameness in schools throughout Ghana showed an estimated prevalence of lameness attributable to poliomyetitis of 5-8 per 1000 school-aged children and an estimated mean annual incidence of paralytic poliomyelitis of 23 per 100 000 population. Official reported incidence rates range from 0-1 to 2-1 per 100 000 population, indicating that at least 90% of cases are not reported. No evidence of epidemics was found to account for these high rates. These suggest that mean annual incidence rates in tropical endemic countries have always been as great, if not greater, than those experienced by temperate countries during epidemic periods in the twentieth century and that the total number of cases of paralytic poliomyelitis occurring in the world each year has been reduced by only 25% since the advent of polio vaccine. Immunisation against poliomyelitis must have a high priority in Ghana and other tropical countries where the disease is endemic.
对加纳全国学校的跛足情况进行的邮政调查显示,每1000名学龄儿童中,估计因小儿麻痹症导致跛足的患病率为5至8例,每10万人中,麻痹性脊髓灰质炎的估计年发病率为23例。官方报告的发病率在每10万人0.1至2.1例之间,这表明至少90%的病例未被报告。未发现有疫情能解释这些高发病率。这些情况表明,热带流行国家的年平均发病率一直与二十世纪温带国家在疫情期间经历的发病率一样高,甚至更高,而且自脊髓灰质炎疫苗问世以来,全世界每年发生的麻痹性脊髓灰质炎病例总数仅减少了25%。在加纳和其他该疾病流行的热带国家,脊髓灰质炎免疫接种必须列为高度优先事项。