荷兰克罗恩病患者的α1-抗胰蛋白酶水平及表型
alpha 1-Antitrypsin-levels and phenotypes in Crohn's disease in the Netherlands.
作者信息
Klasen E C, Biemond I, Weterman I T
出版信息
Gut. 1980 Oct;21(10):840-2. doi: 10.1136/gut.21.10.840.
Abstract
A group of 310 unrelated patients suffering from Crohn's disease has been screened for quantitative and electrophoretic variations of alpha 1-antitrypsin (alpha 1AT). A comparison was made betweeen patients and healthy controls. The distribution of electrophoretic alpha 1AT variants in the patients showed no significant deviation from the controls. The alpha 1AT quantities are significantly higher in the Crohn's disease population than in the controls.
摘要
对一组310名患克罗恩病的非亲属患者进行了α1-抗胰蛋白酶（α1AT）定量和电泳变异筛查。并对患者与健康对照进行了比较。患者中电泳α1AT变异体的分布与对照相比无显著偏差。克罗恩病患者群体中的α1AT量显著高于对照组。
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