罗沙米星和红霉素对一组非发酵革兰氏阴性杆菌的体外活性。
In vitro activity of rosamicin and erythromycin against a group of nonfermenting gram-negative bacilli.
作者信息
DiPersio J R, Krafczyk T L
出版信息
Antimicrob Agents Chemother. 1978 Aug;14(2):274-6. doi: 10.1128/AAC.14.2.274.
Abstract
The in vitro inhibitory activity of rosamicin and erythromycin against 283 strains of nonfermenting, gram-negative bacilli was determined by using a broth dilution procedure. Rosamicin demonstrated greater activity than erythromycin against most strains tested. A number of species demonstrated significantly lower minimum inhibitory concentrations to rosamicin and would fall within the therapeutic range of the drug based on current pharmacological data.
摘要
采用肉汤稀释法测定了蔷薇霉素和红霉素对283株非发酵革兰氏阴性杆菌的体外抑制活性。在大多数测试菌株中，蔷薇霉素显示出比红霉素更强的活性。一些菌种对蔷薇霉素的最低抑菌浓度显著更低，根据当前药理学数据，这些菌种的浓度将处于该药物的治疗范围内。
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本文引用的文献
1
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Antimicrob Agents Chemother. 1974 Mar;5(3):272-5. doi: 10.1128/AAC.5.3.272.
2
A new Micromonospora-produced macrolide antibiotic, rosamicin.一种新的由小单孢菌产生的大环内酯类抗生素，蔷薇霉素。
J Antibiot (Tokyo). 1972 Nov;25(11):641-6. doi: 10.7164/antibiotics.25.641.
3
Biological studies with rosamicin, a new Micromonospora-produced macrolide antibiotic.
J Antibiot (Tokyo). 1972 Nov;25(11):647-52. doi: 10.7164/antibiotics.25.647.
4
Rosamicin: in vitro activity against anaerobes and comparison with erythromycin.蔷薇霉素：对厌氧菌的体外活性及与红霉素的比较
Antimicrob Agents Chemother. 1976 Feb;9(2):350-1. doi: 10.1128/AAC.9.2.350.
5
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6
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