Johnson N M, Brostoff J, Hudspith B N, Boot J R, McNicol M W
Clin Exp Immunol. 1981 Mar;43(3):491-6.
Increased suppressor T gamma lymphocytes have been described in sarcoidosis. We have shown that a proportion of these cells are esterase-positive, phagocytic, adherent to plastic and stain with an anti-monocyte serum. Removal of these cells or the addition of indomethacin increases the lymphocyte transformation to Con A. Transformation was still reduced in spite of preincubation with plastic and the addition of indomethacin suggesting that a further abnormality exists. Thus, within the increased number of T gamma cells there exists a population of activated monocytes which rosette with sheep red blood cells and could therefore be mistaken for T cells.
结节病中已发现抑制性Tγ淋巴细胞增多。我们已经证明，这些细胞中有一部分是酯酶阳性、可吞噬、能黏附于塑料并能用抗单核细胞血清染色的。去除这些细胞或加入消炎痛会增加淋巴细胞对刀豆球蛋白A的转化。尽管经过塑料预处理并加入了消炎痛，但转化率仍然降低，这表明存在进一步的异常情况。因此，在增多的Tγ细胞中，存在一群与绵羊红细胞形成玫瑰花结的活化单核细胞，因此可能会被误认为是T细胞。
