具有IgM Fc受体的新生T淋巴细胞对B淋巴细胞分化的抑制作用。
Suppression of B lymphocyte differentiation by newborn T lymphocytes with an Fc receptor for IgM.
作者信息
Hayward A R, Lydyard P M
出版信息
Clin Exp Immunol. 1978 Dec;34(3):374-8.
Abstract
The IgM (Fc)-binding subpopulation of human newborn T lymphocytes (T) suppressed the pokeweed mitogen induced differentiation of adult B lymphocytes. Positively isolated IgG (Fc)-binding T lymphocytes (T) also suppressed, but lymphocyte preparations negatively enriched for T by the depletion of T cells were not suppressive. The Fc receptor specificity of the human newborn suppressor appears to resemble that of the human Con A suppressor.
摘要
人类新生儿T淋巴细胞（T）的IgM（Fc）结合亚群抑制了商陆丝裂原诱导的成人B淋巴细胞分化。经阳性分离的IgG（Fc）结合T淋巴细胞（T）也具有抑制作用，但通过T细胞耗竭对T进行阴性富集的淋巴细胞制剂则无抑制作用。人类新生儿抑制细胞的Fc受体特异性似乎与人类刀豆蛋白A抑制细胞的Fc受体特异性相似。
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3
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