Liebermann H
Arch Exp Veterinarmed. 1978;32(3):427-34.
Ultracentrifugation has assumed growing importance in virus diagnosis as a technique by which to concentrate and purify viruses for immediacy diagnosis on the basis of electron microscopy as well as for purely virological and serological tests. Ultracentrifugation has proved to be helpful for sizeable improvement of sensitivity for detection, which, in turn, has been conducive to time saving. The preparational ultracentrifuge enables also direct diagnosis by determination of isodensities and sedimentation coefficients of viruses and their components. Examples are mentioned, in that context, such as FMD virus, virus of vesicular swine disease, virus of larynx papillomatosis of man, and goose influenza virus. An account is given of isodensities and sedimentation coefficients of animal viruses.
超速离心在病毒诊断中发挥着越来越重要的作用，它是一种用于浓缩和纯化病毒的技术，可用于基于电子显微镜的即时诊断以及纯病毒学和血清学检测。事实证明，超速离心有助于大幅提高检测灵敏度，进而节省时间。制备型超速离心机还能通过测定病毒及其成分的等密度和沉降系数进行直接诊断。在这方面列举了一些例子，如口蹄疫病毒、猪水疱病病毒、人喉乳头瘤病毒和鹅流感病毒。文中还介绍了动物病毒的等密度和沉降系数。
