Retinal 's' antigen disease in rats.

The form of experimental allergic uveoretinitis induced by sensitization with retinal 's' antigen in rats actually begins as a pars planitis and juxtapapillary choroiditis. Retinal inflammation develops at the middle limiting vascular layer of the retina and extends outward with focal destruction of photoreceptors and inward as a perivasculitis of small retinal vessels. Extensive choroiditis is a late development in severely diseased animals. Significant strain differences in susceptibility to disease were observed.