盘尾丝虫病中的循环抗原-抗体复合物
Circulating antigen-antibody complexes in onchocerciasis.
作者信息
Steward M W, Sisley B, Mackenzie C D, El Sheikh H
出版信息
Clin Exp Immunol. 1982 Apr;48(1):17-24.
Abstract
The presence of circulating antigen-antibody complexes in the sera of patients with onchocerciasis was investigated using the Clq and conglutinin solid-phase binding assays. Only 50% of patients' sera had demonstrable complexes, levels of complexes were unrelated to microfilarial load and specific anti-onchocercal antibody titres and results with the two tests for complexes were not correlated. Both IgM- and IgG-containing complexes were commonly involved but there was no correlation between the levels of complexes containing these isotypes. Evidence for the presence of IgE in complexes of sera from a minority of individuals was also obtained.
摘要
采用Clq固相结合试验和胶固素固相结合试验，对盘尾丝虫病患者血清中循环抗原-抗体复合物的存在情况进行了研究。只有50%的患者血清中有可检测到的复合物，复合物水平与微丝蚴负荷、特异性抗盘尾丝虫抗体滴度无关，两种复合物检测结果也不相关。含有IgM和IgG的复合物都普遍存在，但含有这些同种型的复合物水平之间没有相关性。还获得了少数个体血清复合物中存在IgE的证据。
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本文引用的文献
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