某化工厂员工的尿硫醚
Urinary thioether of employees of a chemical plant.
作者信息
Vainio H, Savolainen H, Kilpikari I
出版信息
Br J Ind Med. 1978 Aug;35(3):232-4. doi: 10.1136/oem.35.3.232.
Abstract
The thiols in the morning urine of 224 employees of a chemical plant were determined after alkaline hydrolysis of all urinary thioethers. The highest thioether excretion was found in rubber workers and radial tyre builders in comparison with clerks, plastic monomer mixers and footwear preparers. Smoking and medication tended to increase thioether excretion. Urinary thioether determination may prove to be a valuable tool in assessing exposure to mixtures of chemicals regardless of the route of absorption.
摘要
对某化工厂224名员工晨尿中的硫醇进行了测定，测定前先对所有尿硫醚进行碱性水解。与职员、塑料单体混合工和鞋类制备工相比，橡胶工人和子午线轮胎制造工人的硫醚排泄量最高。吸烟和用药往往会增加硫醚排泄量。无论吸收途径如何，尿硫醚测定可能是评估化学物质混合物暴露情况的一种有价值的工具。
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