Thuriaux M C
Trop Geogr Med. 1982 Jun;34(2):163-8.
An investigation of lower limb motor disorders among school-age children in Niger has shown a prevalence rate of seven per thousand in this age group. Sequelae of poliomyelitis, the major group among these disorders, show no significant difference according to sex or to school attendance status. Eight per cent of children suffering from poliomyelitis sequelae are unable to work and a further eight per cent need crutches or other aids. Patient histories indicate that over 90% of cases occurred before the child's fourth birthday. Extrapolation from the observed data indicate a tentative annual incidence rate for paralytic poliomyelitis in the order of 45 per 100,000, a figure seven to ten times higher than the figures gathered from routine notifications of poliomyelitis in Niger. The total number of those unable to walk unaided among children under 15 can be estimated in 1981 at 1600, half of whom are unable to walk at all. Trauma to peripheral nerves after intramuscular injections, usually of quinine salts, is second only to poliomyelitis as a cause of lower limb motor disorders.
对尼日尔学龄儿童下肢运动障碍的一项调查显示,该年龄组的患病率为千分之七。小儿麻痹后遗症是这些障碍中的主要类型,在性别或上学情况方面无显著差异。患有小儿麻痹后遗症的儿童中,8%无法正常行走,另有8%需要拐杖或其他辅助器械。病历表明,超过90%的病例发生在儿童4岁生日之前。根据观察数据推断,麻痹性脊髓灰质炎的暂定年发病率约为十万分之45,这一数字比尼日尔脊髓灰质炎常规报告收集的数字高7至10倍。据估计,1981年15岁以下无法独立行走的儿童总数为1600人,其中一半根本无法行走。肌肉注射(通常注射奎宁盐)后导致的外周神经损伤是仅次于小儿麻痹症的下肢运动障碍病因。