Walton E F, Pringle J R
Arch Microbiol. 1980 Feb;124(2-3):285-7. doi: 10.1007/BF00427739.
The resistance of exponentially growing yeast cells to killing by exposure to 52 degrees C increase markedly as the growth temperature was increased. Identical killing curves were obtained for cells suspended in growth medium or in 0.9% saline. Cells resistant to killing at 52 degrees C were quite sensitive to killing at slightly higher temperatures. These results suggest a primary role for membrane damage in the mechanism of heat killing.
指数生长的酵母细胞暴露于52℃时的热致死抗性，会随着生长温度的升高而显著增加。无论是悬浮在生长培养基还是0.9%盐溶液中的细胞，都能得到相同的致死曲线。对52℃热致死具有抗性的细胞，在略高温度下对热致死相当敏感。这些结果表明，膜损伤在热致死机制中起主要作用。
