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通过尿液分析代谢物评估有机溶剂暴露情况（作者译）

[Evaluation of the exposure to organic solvents by means of urinalysis for metabolites (author's transl)].

作者信息

Ikeda M, Hara I

出版信息

Sangyo Igaku. 1980 Jan;22(1):3-17. doi: 10.1539/joh1959.22.3.

DOI:10.1539/joh1959.22.3
PMID:6991742
Abstract

The method of biological monitoring of the exposure to organic solvents by means of urinalysis is discussed. The topics include the variety of the solvents to which the method of monitoring is applicable, choice of time for urine sampling, possible correction of the results for urine density, and establishment of the biological threshold. Recent progress is reviewed in particular, in the cases of benzene, toluene, xylenes, styrene, trichloroethylene, tetrachloroethylene and 1, 1, 1-trichloroethane.

摘要

本文讨论了通过尿液分析对有机溶剂暴露进行生物监测的方法。主题包括该监测方法适用的溶剂种类、尿液采样时间的选择、尿液密度对结果的可能校正以及生物阈值的确定。特别回顾了在苯、甲苯、二甲苯、苯乙烯、三氯乙烯、四氯乙烯和1,1,1-三氯乙烷等情况下的最新进展。

相似文献

1
[Evaluation of the exposure to organic solvents by means of urinalysis for metabolites (author's transl)].通过尿液分析代谢物评估有机溶剂暴露情况（作者译）
Sangyo Igaku. 1980 Jan;22(1):3-17. doi: 10.1539/joh1959.22.3.
2
Whole-body autoradiography and allied tracer techniques in distribution and elimination studies of some organic solvents: benzene, toluene, xylene, styrene, methylene chloride, chloroform, carbon tetrachloride and trichloroethylene.全身放射自显影及相关示踪技术在某些有机溶剂（苯、甲苯、二甲苯、苯乙烯、二氯甲烷、氯仿、四氯化碳和三氯乙烯）分布与消除研究中的应用
Scand J Work Environ Health. 1979;5 Suppl 1:1-263.
3
Hippuric acid, phenol, and trichloroacetic acid levels in the urine of Japanese subjects with no known exposure to organic solvents.未接触过已知有机溶剂的日本受试者尿液中的马尿酸、苯酚和三氯乙酸水平。
Br J Ind Med. 1969 Apr;26(2):162-4. doi: 10.1136/oem.26.2.162.
4
Application and results of whole-body autoradiography in distribution studies of organic solvents.
Crit Rev Toxicol. 1983;12(1):59-118. doi: 10.3109/10408448309029318.
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Estimation of recent exposures to volatile organic chemicals using alveolar air measurements.
Toxicol Ind Health. 1996 Mar-Apr;12(2):201-10.
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[Indices of biological monitoring, with special reference to urinalysis of metabolites of organic solvents].[生物监测指标，特别参考有机溶剂代谢物的尿液分析]
Sangyo Igaku. 1985 Jul;27(4):229-41. doi: 10.1539/joh1959.27.229.
7
Simultaneous determination by gas chromatography of the major metabolites in urine of toluene, xylenes and styrene.气相色谱法同时测定尿液中甲苯、二甲苯和苯乙烯的主要代谢物
Br J Ind Med. 1978 Feb;35(1):56-60. doi: 10.1136/oem.35.1.56.
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Quantitative determination of urinary metabolites in subjects exposed to organic solvents.
Acta Med Okayama. 1981 Dec;35(6):385-94. doi: 10.18926/AMO/31262.
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[Hippuric acid and methylhippuric acid in urine].[尿中的马尿酸和甲基马尿酸]
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[Occupational chronic exposure to organic solvents. II. Toluene concentrations in blood and excretion rates of metabolites in urine in the supervision of printing-workers (author's transl)].[职业性长期接触有机溶剂。II. 印刷工人职业健康监护中血液甲苯浓度及尿中代谢产物排泄率（作者译）]
Int Arch Arbeitsmed. 1973;31(4):265-76.

引用本文的文献

1
Effects of smoking and drinking on excretion of hippuric acid among toluene-exposed workers.吸烟和饮酒对甲苯暴露工人马尿酸排泄的影响。
Int Arch Occup Environ Health. 1993;64(6):425-30. doi: 10.1007/BF00517948.
2
Exposure-excretion relationship of styrene and acetone in factory workers: a comparison of a lipophilic solvent and a hydrophilic solvent.工厂工人中苯乙烯和丙酮的暴露-排泄关系：亲脂性溶剂和亲水性溶剂的比较
Arch Environ Contam Toxicol. 1993 Jul;25(1):129-33. doi: 10.1007/BF00230723.
3
A study on biological monitoring of n-hexane exposure.
一项关于正己烷暴露生物监测的研究。
Int Arch Occup Environ Health. 1983;51(3):253-60. doi: 10.1007/BF00377756.
4
Determination of catechol and quinol in the urine of workers exposed to benzene.接触苯的工人尿液中儿茶酚和对苯二酚的测定。
Br J Ind Med. 1988 Jul;45(7):487-92. doi: 10.1136/oem.45.7.487.
5
Mutual metabolic suppression between benzene and toluene in man.人体中苯和甲苯之间的相互代谢抑制作用。
Int Arch Occup Environ Health. 1988;60(1):15-20. doi: 10.1007/BF00409373.
6
Urinary t,t-muconic acid as an indicator of exposure to benzene.尿中反式，反式-粘康酸作为苯暴露的指标。
Br J Ind Med. 1989 Feb;46(2):122-7. doi: 10.1136/oem.46.2.122.
7
Excretion of 1,2,4-benzenetriol in the urine of workers exposed to benzene.接触苯的工人尿液中1,2,4-苯三酚的排泄情况。
Br J Ind Med. 1989 Aug;46(8):559-65. doi: 10.1136/oem.46.8.559.
8
Urinary methylhippuric acid isomer levels after occupational exposure to a xylene mixture.职业性接触二甲苯混合物后尿中甲基马尿酸异构体水平
Int Arch Occup Environ Health. 1991;63(1):69-75. doi: 10.1007/BF00406201.
9
Dose-dependent increase in 2,5-hexanedione in the urine of workers exposed to n-hexane.接触正己烷的工人尿液中2,5-己二酮呈剂量依赖性增加。
Int Arch Occup Environ Health. 1991;63(4):285-91. doi: 10.1007/BF00386379.
10
Monitoring of workers exposed to a mixture of toluene, styrene and methanol vapours by means of diffusive air sampling, blood analysis and urinalysis.通过扩散式空气采样、血液分析和尿液分析对接触甲苯、苯乙烯和甲醇蒸气混合物的工人进行监测。
Int Arch Occup Environ Health. 1992;63(6):429-35. doi: 10.1007/BF00386940.