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大肠杆菌中核糖体蛋白L10和L7/12合成的自体调控

Autogenous regulation of the synthesis of ribosomal proteins, L10 and L7/12, in Escherichia coli.

作者信息

Fukuda R

出版信息

Mol Gen Genet. 1980;178(2):483-6. doi: 10.1007/BF00270505.

Abstract

The in vitro synthesis of Escherichia coli ribosomal proteins, L10 and L7/12, is specifically repressed by the addition of the L10-L7/12 complex, while that of other ribosomal proteins encoded by the neighboring operons is not affected. Thus the expression of the rpoBC operon is controlled by two autorepression systems, one for the two ribosomal proteins and the other for RNA polymerase beta and beta' subunits, both operating probably at the translational level.

摘要

大肠杆菌核糖体蛋白L10和L7/12的体外合成会因添加L10-L7/12复合物而受到特异性抑制,而相邻操纵子编码的其他核糖体蛋白的合成则不受影响。因此,rpoBC操纵子的表达受两个自动抑制系统控制,一个针对这两种核糖体蛋白,另一个针对RNA聚合酶β和β'亚基,两者可能都在翻译水平起作用。

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