Robakis N, Meza-Basso L, Brot N, Weissbach H
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4261-4. doi: 10.1073/pnas.78.7.4261.
A simplified DNA-directed in vitro system has been developed to study the regulation of the synthesis of ribosomal protein L10 by measuring the formation of the first dipeptide, fMet-Ala. The results show that the inhibition of L10 synthesis by L10 (autoregulation) occurs at or prior to the formation of the first peptide bond.
为了通过测量首个二肽fMet-Ala的形成来研究核糖体蛋白L10合成的调控,已开发出一种简化的DNA指导体外系统。结果表明,L10对L10合成的抑制(自动调控)发生在首个肽键形成之时或之前。