Brodan V, Fabián J, Andĕl M, Tomková D
Czech Med. 1978;1(1):53-61.
In nine patients with ischaemic heart disease at rest and during pacing differences of free plasma amino acids, lactate, ammonia and uric acid between arterial blood and blood in the coronary sinus (a-cs differences) were investigated. At rest one single significant difference was found, i.e. a positive a-cs difference in aspartate. During pacing significant positive differences were recorded in aspartate, glutamate, leucine and isoleucine and significant negative a-cs differences in cystine-cysteine, glutamine and aspartic acid and in alanine. Among the correlations between a-cs differences the negative relationship between lactate and alanine and the negative correlation between cystine-cysteine and leucine, isoleucine and glutamine is significant. There is a positive relationship between the a-cs difference of alanine and glutamine and between the differences of leucine, isoleucine and glutamate. The a-cs differences of ammonia and uric acid correlate negatively.
对9例静息及起搏状态下的缺血性心脏病患者，研究了动脉血与冠状窦血之间游离血浆氨基酸、乳酸、氨及尿酸的差异（a-cs差异）。静息时仅发现1个显著差异，即天冬氨酸的a-cs差异为正值。起搏时，天冬氨酸、谷氨酸、亮氨酸和异亮氨酸的a-cs差异显著为正，胱氨酸-半胱氨酸、谷氨酰胺、天冬氨酸及丙氨酸的a-cs差异显著为负。在a-cs差异之间的相关性中，乳酸与丙氨酸之间的负相关以及胱氨酸-半胱氨酸与亮氨酸、异亮氨酸和谷氨酰胺之间的负相关显著。丙氨酸与谷氨酰胺的a-cs差异之间以及亮氨酸、异亮氨酸与谷氨酸的差异之间呈正相关。氨和尿酸的a-cs差异呈负相关。
