健康家养犬粪便菌群中R质粒的发生率。
Incidence of R-plasmids in fecal flora of healthy household dogs.
作者信息
Hirsh D C, Ling G V, Ruby A L
出版信息
Antimicrob Agents Chemother. 1980 Mar;17(3):313-5. doi: 10.1128/AAC.17.3.313.
Rectal swabs were taken from healthy household dogs that, insofar as could be determined, had not received antimicrobial drugs. Tetracycline-resistant coliforms comprised 80 to 100% of the total number of coliforms in 61 (65%) of the 94 dogs sampled. The median number of other resistance determinants possessed by these tetracycline-resistant coliforms was 5.1. Of the tetracycline-resistant strains studied, 97% were resistant to streptomycin; 76% were resistant to sulfonamides; 59% were resistant to ampicillin; 59% were resistant to kanamycin/neomycin; and 40% were resistant to chloramphenicol. A total of 64% of the strains was shown to transfer resistance by conjugation or by the aid of the sex factor F. Of the strains transferring resistance, 33% were found to transfer all of their resistance determinants.
从健康的家养犬采集直肠拭子，据判断，这些犬未接受过抗菌药物治疗。在94只采样犬中，61只（65%）的四环素抗性大肠菌群占大肠菌群总数的80%至100%。这些四环素抗性大肠菌群拥有的其他抗性决定因素的中位数为5.1。在所研究的四环素抗性菌株中，97%对链霉素耐药；76%对磺胺类药物耐药；59%对氨苄青霉素耐药；59%对卡那霉素/新霉素耐药；40%对氯霉素耐药。总共64%的菌株通过接合或借助性因子F传递耐药性。在传递耐药性的菌株中，33%被发现传递其所有的抗性决定因素。
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