Kozinski A W, Ling S K, Hutchinson N, Halpern M E, Mattson T
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5064-8. doi: 10.1073/pnas.77.9.5064.
Under various conditions, specific genetic areas of the phage T4 DNA molecule are preferentially and repeatedly replicated, resulting in the amplification of these areas. These areas are found to lie in the vicinity of the known origins of DNA replication.
在各种条件下,噬菌体T4 DNA分子的特定基因区域会优先且反复地进行复制,从而导致这些区域的扩增。发现这些区域位于已知的DNA复制起点附近。