Owerbach D, Bell G I, Rutter W J, Brown J A, Shows T B
Diabetes. 1981 Mar;30(3):267-70. doi: 10.2337/diab.30.3.267.
The human insulin gene has been previously localized to chromosome 11. We have analyzed the human DNA sequences present in a human-mouse somatic cell hybrid line possessing a translocation involving human chromosomes 11 and X. These data indicate that the human insulin gene is located on the short arm of chromosome 11 in the region p13 leads to pter.
人类胰岛素基因先前已被定位到11号染色体上。我们分析了一个人鼠体细胞杂种细胞系中的人类DNA序列,该杂种细胞系具有涉及人类11号染色体和X染色体的易位。这些数据表明,人类胰岛素基因位于11号染色体短臂上,在p13至pter区域。