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肾移植术后10年乙肝表面抗原血症观察

Observations on 10 years' HBs antigenaemia after renal transplantation.

作者信息

Nagington J

出版信息

J Clin Pathol. 1981 Apr;34(4):412-3. doi: 10.1136/jcp.34.4.412.

Abstract

A renal transplant patient became a carrier of HBs Ag within four weeks of a successful transplant. The level of antigenaemia was extremely high, and approximately 3% of the particles were 42 nm Dane particles, although the anti-HBe was present from at least 20 months after transplant. After four years the antigenaemia declined to a low level, and five years later HBs Ag became undetectable for the first time. During the past 18 months, no antigen has been detected although immunosuppression continues and the original kidney is still functional.

摘要

一名肾移植患者在成功移植后的四周内成为乙肝表面抗原(HBs Ag)携带者。抗原血症水平极高,尽管移植后至少20个月就出现了乙肝e抗体(anti-HBe),但约3%的颗粒是42纳米的 Dane颗粒。四年后,抗原血症降至低水平,五年后乙肝表面抗原首次检测不到。在过去的18个月里,尽管免疫抑制仍在继续且原肾仍有功能,但未检测到抗原。

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