青霉素对A组链球菌的影响：活力丧失似乎先于脂磷壁酸释放的刺激。
Effects of penicillin on group A streptococci: loss of viability appears to precede stimulation of release of lipoteichoic acid.
作者信息
Kessler R E, van de Rijn I
出版信息
Antimicrob Agents Chemother. 1981 Jan;19(1):39-43. doi: 10.1128/AAC.19.1.39.
Abstract
The rate of killing of a group A streptococcal species by penicillin was compared with the release of lipoteichoic acid (LTA) and its deacylated derivative, dLTA. Although there was no stimulation of release from stationary-phase cells in the presence of penicillin, there was dramatic release of LTA and dLTA from exponential-phase cells after the addition of penicillin. Although decreases in viability were observed within 15 min after addition of penicillin, culture mass and LTA content did not appear to be affected until after 30 min. Stimulation of release of LTA and dLTA appeared to take place after 15 but before 30 min after addition of penicillin. These observations are interpreted to indicate that the stimulation of release of LTA and dLTA in response to penicillin is secondary to the killing event.
摘要
将青霉素对A组链球菌的杀菌速率与脂磷壁酸（LTA）及其脱酰基衍生物dLTA的释放情况进行了比较。尽管在青霉素存在的情况下，稳定期细胞的释放未受到刺激，但加入青霉素后，对数期细胞会大量释放LTA和dLTA。虽然在加入青霉素后15分钟内观察到存活率下降，但直到30分钟后培养物质量和LTA含量才似乎受到影响。LTA和dLTA的释放刺激似乎在加入青霉素后15分钟但在30分钟之前发生。这些观察结果被解释为表明青霉素诱导的LTA和dLTA释放刺激是杀菌事件的继发结果。
相似文献
1
Effects of penicillin on group A streptococci: loss of viability appears to precede stimulation of release of lipoteichoic acid.青霉素对A组链球菌的影响：活力丧失似乎先于脂磷壁酸释放的刺激。
Antimicrob Agents Chemother. 1981 Jan;19(1):39-43. doi: 10.1128/AAC.19.1.39.
2
Release of fibronectin-lipoteichoic acid complexes from group A streptococci with penicillin.用青霉素从A组链球菌中释放纤连蛋白-脂磷壁酸复合物
Infect Immun. 1986 Feb;51(2):529-35. doi: 10.1128/iai.51.2.529-535.1986.
3
Excretion of lipoteichoic acid by group A streptococci. Influence of penicillin on excretion and loss of ability to adhere to human oral mucosal cells.A 组链球菌脂磷壁酸的排泄。青霉素对排泄及黏附人口腔黏膜细胞能力丧失的影响。
J Clin Invest. 1978 Mar;61(3):671-7. doi: 10.1172/JCI108979.
4
Comparative analysis of the localization of lipoteichoic acid in Streptococcus agalactiae and Streptococcus pyogenes.无乳链球菌和化脓性链球菌中脂磷壁酸定位的比较分析。
Infect Immun. 1987 Oct;55(10):2383-6. doi: 10.1128/iai.55.10.2383-2386.1987.
5
Characteristics of the binding of streptococcal lipoteichoic acid to human oral epithelial cells.链球菌脂磷壁酸与人口腔上皮细胞结合的特性
J Infect Dis. 1980 Apr;141(4):457-62. doi: 10.1093/infdis/141.4.457.
6
Characterization and localization of the enzymatic deacylation of lipoteichoic acid in group A streptococci.A组链球菌中脂磷壁酸酶促脱酰作用的特性与定位
J Exp Med. 1979 Dec 1;150(6):1498-509. doi: 10.1084/jem.150.6.1498.
7
Formation of molecular complexes between a structurally defined M protein and acylated or deacylated lipoteichoic acid of Streptococcus pyogenes.化脓性链球菌结构明确的M蛋白与酰化或去酰化脂磷壁酸之间分子复合物的形成。
J Bacteriol. 1982 Feb;149(2):426-33. doi: 10.1128/jb.149.2.426-433.1982.
8
Streptococcus pyogenes clinical isolates and lipoteichoic acid.化脓性链球菌临床分离株与脂磷壁酸
Infect Immun. 1990 Nov;58(11):3779-87. doi: 10.1128/iai.58.11.3779-3787.1990.
9
Fatty acid binding sites of serum albumin as membrane receptor analogs for streptococcal lipoteichoic acid.血清白蛋白的脂肪酸结合位点作为链球菌脂磷壁酸的膜受体类似物。
Infect Immun. 1980 Jul;29(1):119-22. doi: 10.1128/iai.29.1.119-122.1980.
10
Hybridoma antibodies to the lipid-binding site(s) in the amino-terminal region of fibronectin inhibits binding of streptococcal lipoteichoic acid.针对纤连蛋白氨基末端区域脂质结合位点的杂交瘤抗体可抑制链球菌脂磷壁酸的结合。
J Infect Dis. 1987 Aug;156(2):344-9. doi: 10.1093/infdis/156.2.344.
引用本文的文献
1
Glucan-binding factor in saliva.唾液中的葡聚糖结合因子。
Infect Immun. 1988 Nov;56(11):2912-7. doi: 10.1128/iai.56.11.2912-2917.1988.
2
Effects of medium composition on penicillin-induced hydrolysis and loss of RNA and culture turbidity in group A streptococci.培养基成分对A组链球菌中青霉素诱导的RNA水解、RNA损失及培养物浊度的影响。
J Bacteriol. 1989 Dec;171(12):6668-73. doi: 10.1128/jb.171.12.6668-6673.1989.
3
Correlation of penicillin-induced lysis of Enterococcus faecium with saturation of essential penicillin-binding proteins and release of lipoteichoic acid.青霉素诱导的屎肠球菌裂解与必需青霉素结合蛋白的饱和及脂磷壁酸释放的相关性
Antimicrob Agents Chemother. 1990 Oct;34(10):1901-7. doi: 10.1128/AAC.34.10.1901.
本文引用的文献
1
ANTIGEN-ANTIBODY CROSSED ELECTROPHORESIS.抗原-抗体交叉电泳
Anal Biochem. 1965 Feb;10:358-61. doi: 10.1016/0003-2697(65)90278-2.
2
Growth characteristics of group A streptococci in a new chemically defined medium.A组链球菌在一种新的化学成分明确的培养基中的生长特性。
Infect Immun. 1980 Feb;27(2):444-8. doi: 10.1128/iai.27.2.444-448.1980.
3
Inhibition of peptidoglycan, ribonucleic acid, and protein synthesis in tolerant strains of Streptococcus mutans.变形链球菌耐受菌株中肽聚糖、核糖核酸和蛋白质合成的抑制作用
Antimicrob Agents Chemother. 1980 Apr;17(4):572-82. doi: 10.1128/AAC.17.4.572.
4
Comparative studies on the isolation of membrane lipoteichoic acid from Lactobacillus fermenti.从发酵乳杆菌中分离膜脂磷壁酸的比较研究。
J Bacteriol. 1973 Jan;113(1):365-72. doi: 10.1128/jb.113.1.365-372.1973.
5
Isolation and characterization of a mutant of Staphylococcus aureus deficient in autolytic activity.金黄色葡萄球菌自溶活性缺陷突变体的分离与鉴定
J Bacteriol. 1976 Mar;125(3):961-7. doi: 10.1128/jb.125.3.961-967.1976.
6
Tolerant response of Streptococcus sanguis to beta-lactams and other cell wall inhibitors.血链球菌对β-内酰胺类及其他细胞壁抑制剂的耐受性反应。
Antimicrob Agents Chemother. 1977 May;11(5):888-96. doi: 10.1128/AAC.11.5.888.
7
Effect of lipoteichoic acid and lipids on lysis of intact cells of Streptococcus faecalis.脂磷壁酸和脂质对粪肠球菌完整细胞裂解的影响。
J Bacteriol. 1976 Sep;127(3):1582-4. doi: 10.1128/jb.127.3.1582-1584.1976.
8
Release of lipoteichoic acid from Streptococcus sanguis: stimulation of release during penicillin treatment.血链球菌中脂磷壁酸的释放：青霉素治疗期间释放的刺激作用。
J Bacteriol. 1979 Mar;137(3):1180-4. doi: 10.1128/jb.137.3.1180-1184.1979.
9
Characterization and localization of the enzymatic deacylation of lipoteichoic acid in group A streptococci.A组链球菌中脂磷壁酸酶促脱酰作用的特性与定位
J Exp Med. 1979 Dec 1;150(6):1498-509. doi: 10.1084/jem.150.6.1498.
10
Excretion of lipoteichoic acid by group A streptococci. Influence of penicillin on excretion and loss of ability to adhere to human oral mucosal cells.A 组链球菌脂磷壁酸的排泄。青霉素对排泄及黏附人口腔黏膜细胞能力丧失的影响。
J Clin Invest. 1978 Mar;61(3):671-7. doi: 10.1172/JCI108979.
Zotero 插件