Suppr超能文献

来自大肠杆菌、玉米叶绿体以及人类和小鼠线粒体核糖体的大亚基核糖体RNA的二级结构。

Secondary structure of the large subunit ribosomal RNA from Escherichia coli, Zea mays chloroplast, and human and mouse mitochondrial ribosomes.

作者信息

Glotz C, Zwieb C, Brimacombe R, Edwards K, Kössel H

出版信息

Nucleic Acids Res. 1981 Jul 24;9(14):3287-306. doi: 10.1093/nar/9.14.3287.

Abstract

Short base-paired RNA fragments, and fragments containing intra-RNA cross-links, were isolated from E. coli 23S rRNA or 50S ribosomal subunits by two-dimensional gel electrophoresis. The interactions thus found were used as a first basis for constructing a secondary structure model of the 23S rRNA. Sequence comparison with the 23S rDNA from Z. mays chloroplasts, as well as with the 16S (large subunit) rDNA from human and mouse mitochondria, enabled the experimental model to be improved and extrapolated to give complete secondary structures of all four species. The structures are organized in well-defined domains, with over 450 compensating base changes between the two 23S species. Some ribosomal structural "'switches" were found, one involving 5S rRNA.

摘要

通过二维凝胶电泳从大肠杆菌23S rRNA或50S核糖体亚基中分离出短的碱基配对RNA片段以及含有RNA内交联的片段。由此发现的相互作用被用作构建23S rRNA二级结构模型的首要依据。与玉米叶绿体的23S rDNA以及人类和小鼠线粒体的16S(大亚基)rDNA进行序列比较,使得实验模型得以改进并外推,从而得出所有这四个物种的完整二级结构。这些结构由明确界定的结构域组成,两个23S物种之间有超过450个补偿性碱基变化。还发现了一些核糖体结构“开关”,其中一个涉及5S rRNA。

相似文献

6
Secondary structure model for 23S ribosomal RNA.23S核糖体RNA的二级结构模型
Nucleic Acids Res. 1981 Nov 25;9(22):6167-89. doi: 10.1093/nar/9.22.6167.

引用本文的文献

6
Secondary structure and domain architecture of the 23S and 5S rRNAs.23S 和 5S rRNA 的二级结构和结构域结构。
Nucleic Acids Res. 2013 Aug;41(15):7522-35. doi: 10.1093/nar/gkt513. Epub 2013 Jun 14.
7
Mechanism of protein biosynthesis in mammalian mitochondria.哺乳动物线粒体中蛋白质生物合成的机制。
Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):1035-54. doi: 10.1016/j.bbagrm.2011.11.009. Epub 2011 Dec 7.
10
Evolutionary rates vary among rRNA structural elements.rRNA的各个结构元件的进化速率各不相同。
Nucleic Acids Res. 2007;35(10):3339-54. doi: 10.1093/nar/gkm101. Epub 2007 Apr 27.

本文引用的文献

10
A 5.8 S rRNA-like sequence in prokaryotic 23 S rRNA.原核生物23S rRNA中的一段5.8S rRNA样序列。
FEBS Lett. 1980 Oct 6;119(2):212-4. doi: 10.1016/0014-5793(80)80254-7.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验