小鼠和大鼠中索状因子的佐剂活性（免疫诱导特性）。
Adjuvanticity (immunity-inducing property) of cord factor in mice and rats.
作者信息
Saito R, Nagao S, Takamoto M, Sugiyama K, Tanaka A
出版信息
Infect Immun. 1977 Jun;16(3):725-9. doi: 10.1128/iai.16.3.725-729.1977.
Abstract
Cord factor, a glycolipid in mycobacteria, was found to make a tolerogenic protein antigen immunogenic when injected 0 to 2 days before tolerogen injection in mice and rats. Cord factor was also found to increase phagocytic function of the reticuloendothelial system of mice, and the relationship between the immunity-inducing capacity and the phagocytic function is discussed.
摘要
索状因子是分枝杆菌中的一种糖脂，研究发现，在小鼠和大鼠体内，于耐受原注射前0至2天注射索状因子，可使耐受性蛋白抗原具有免疫原性。还发现索状因子可增强小鼠网状内皮系统的吞噬功能，并对免疫诱导能力与吞噬功能之间的关系进行了讨论。
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