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血清谷氨酸脱氢酶并非酗酒者肝细胞坏死的可靠标志物。

Serum glutamate dehydrogenase is not a reliable marker of liver cell necrosis in alcoholics.

作者信息

Jenkins W J, Rosalki S B, Foo Y, Scheuer P J, Nemesanszky E, Sherlock S

出版信息

J Clin Pathol. 1982 Feb;35(2):207-10. doi: 10.1136/jcp.35.2.207.

Abstract

Serum glutamate dehydrogenase (EC 1.4.1.3.) activity was measured in 73 hospital patients who had a history of chronic alcohol abuse and who all had a liver biopsy performed. High levels of serum GDH activity occurred in those patients with recent excess alcohol consumption independently of the underlying liver histology, and did not discriminate between those patients with and those without alcoholic hepatitis.

摘要

对73名有慢性酒精滥用史且均接受了肝活检的住院患者测定了血清谷氨酸脱氢酶(EC 1.4.1.3.)活性。近期过量饮酒的患者出现了高水平的血清GDH活性,这与潜在的肝脏组织学无关,并且无法区分患有和未患有酒精性肝炎的患者。

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Serum glutamate dehydrogenase in alcoholic liver disease.酒精性肝病中的血清谷氨酸脱氢酶
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引用本文的文献

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Clinical pathology of alcohol.酒精的临床病理学
J Clin Pathol. 1983 Apr;36(4):365-78. doi: 10.1136/jcp.36.4.365.
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Clinical use of serum enzymes in liver disease.血清酶在肝脏疾病中的临床应用。
Dig Dis Sci. 1988 Dec;33(12):1601-14. doi: 10.1007/BF01535953.

本文引用的文献

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Serum -glutamyl transpeptidase activity in alcoholism.酗酒者血清γ-谷氨酰转肽酶活性
Clin Chim Acta. 1972 Jun;39(1):41-7. doi: 10.1016/0009-8981(72)90297-5.

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