Holt S, Reid J, Taylor T V, Tothill P, Heading R C
Gut. 1982 Apr;23(4):292-6. doi: 10.1136/gut.23.4.292.
The influence of the type and size of solid particles on their emptying from the stomach was studied using isotopically labelled chicken liver and inert particles in normal subjects and in patients who had undergone gastric surgery. In normal subjects, initial emptying of the liver was slower than that of inert particles both for large liver cubes (1 cm) and small cubes (0.3 cm). Liver emptying subsequently accelerated to be faster than emptying of the inert particles. Overall emptying of the liver given as small cubes was faster than large cubes; 50% emptied in 50 minutes and 70 minutes respectively. In the postoperative subjects, emptying of the liver and of the inert particles was identical. The findings are consistent with the hypothesis that solid foods such as liver are ground down and 'liquified' by the action of gastric peristalsis before being discharged to the duodenum. Ingested particle size appears to influence the rapidity of this process, which should be distinguished from the propulsive function of the stomach where small solid particles are concerned.
利用同位素标记的鸡肝和惰性颗粒，在正常受试者和接受过胃部手术的患者中研究了固体颗粒的类型和大小对其从胃中排空的影响。在正常受试者中，无论是大的肝块（1厘米）还是小的肝块（0.3厘米），肝脏的初始排空都比惰性颗粒慢。肝脏排空随后加速，比惰性颗粒的排空更快。小方块状肝脏的总体排空比大方块状快；分别在50分钟和70分钟内排空50%。在术后受试者中，肝脏和惰性颗粒的排空是相同的。这些发现与以下假设一致，即肝脏等固体食物在排入十二指肠之前，会通过胃蠕动的作用被磨碎并“液化”。摄入颗粒的大小似乎会影响这个过程的速度，这与涉及小固体颗粒时胃的推进功能不同。
