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Scintigraphic validation of a magnetic resonance imaging method to study gastric emptying of a solid meal in humans.

作者信息

Feinle C, Kunz P, Boesiger P, Fried M, Schwizer W

机构信息

Department of Internal Medicine, Division of Gastroenterology, University Hospital Zürich, Switzerland.

出版信息

Gut. 1999 Jan;44(1):106-11. doi: 10.1136/gut.44.1.106.

Abstract

BACKGROUND

We have previously used a magnetic resonance imaging (MRI) method to study gastric emptying of liquids. So far, however, it has not possible to assess solid gastric emptying with this technique.

AIMS

To validate scintigraphically MRI as a method for measuring emptying of a mixed solid/liquid meal.

METHODS

In eight healthy subjects, gastric emptying of a solid/liquid (SM) and a liquid meal (LM) of identical energy content and macronutrient composition was studied by scintigraphy and MRI for 120 minutes.

RESULTS

MRI and scintigraphy agreed with respect to emptying profiles (intraclass correlation coefficient (RI) SM: 0.988, RI, LM: 0.917), t1/2 (SMMRI: 129 (9), SMScinti: 123 (11) minutes, NS; LMMRI: 100 (7), LMScinti: 110 (8) minutes, NS) and AUC (SMMRI: 8999 (232), SMScinti: 8788 (277) min%, NS; LMMRI: 8819 (368), LMScinti: 8891 (321) min%, NS).

CONCLUSIONS

MRI can be used to measure reliably gastric emptying not only of liquid but also of mixed solid/liquid meals in humans.

摘要

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