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一种用于研究人体固体食物胃排空的磁共振成像方法的闪烁显像验证。

Scintigraphic validation of a magnetic resonance imaging method to study gastric emptying of a solid meal in humans.

作者信息

Feinle C, Kunz P, Boesiger P, Fried M, Schwizer W

机构信息

Department of Internal Medicine, Division of Gastroenterology, University Hospital Zürich, Switzerland.

出版信息

Gut. 1999 Jan;44(1):106-11. doi: 10.1136/gut.44.1.106.

DOI:10.1136/gut.44.1.106
PMID:9862835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1760059/
Abstract

BACKGROUND

We have previously used a magnetic resonance imaging (MRI) method to study gastric emptying of liquids. So far, however, it has not possible to assess solid gastric emptying with this technique.

AIMS

To validate scintigraphically MRI as a method for measuring emptying of a mixed solid/liquid meal.

METHODS

In eight healthy subjects, gastric emptying of a solid/liquid (SM) and a liquid meal (LM) of identical energy content and macronutrient composition was studied by scintigraphy and MRI for 120 minutes.

RESULTS

MRI and scintigraphy agreed with respect to emptying profiles (intraclass correlation coefficient (RI) SM: 0.988, RI, LM: 0.917), t1/2 (SMMRI: 129 (9), SMScinti: 123 (11) minutes, NS; LMMRI: 100 (7), LMScinti: 110 (8) minutes, NS) and AUC (SMMRI: 8999 (232), SMScinti: 8788 (277) min%, NS; LMMRI: 8819 (368), LMScinti: 8891 (321) min%, NS).

CONCLUSIONS

MRI can be used to measure reliably gastric emptying not only of liquid but also of mixed solid/liquid meals in humans.

摘要

背景

我们之前曾使用磁共振成像(MRI)方法研究液体的胃排空情况。然而,迄今为止,用该技术尚无法评估固体的胃排空。

目的

通过闪烁扫描法验证MRI作为测量固体/液体混合餐排空的一种方法。

方法

对8名健康受试者,采用闪烁扫描法和MRI研究能量含量及常量营养素组成相同的固体/液体餐(SM)和液体餐(LM)的胃排空情况,持续120分钟。

结果

MRI和闪烁扫描法在排空曲线方面一致(组内相关系数(RI),SM:0.988,RI,LM:0.917),t1/2(SM,MRI:129(9)分钟,SM,闪烁扫描法:123(11)分钟,无显著差异;LM,MRI:100(7)分钟,LM,闪烁扫描法:110(8)分钟,无显著差异)以及AUC(SM,MRI:8999(232),SM,闪烁扫描法:8788(277)分钟%,无显著差异;LM,MRI:8819(368),LM,闪烁扫描法:8891(321)分钟%,无显著差异)。

结论

MRI不仅可用于可靠测量人体液体的胃排空,还可用于测量固体/液体混合餐的胃排空。

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