使用Lewis肺癌建立肝转移形成的实验模型。
Experimental model for liver metastasis formation using Lewis lung tumor.
作者信息
Kopper L, Van Hanh T, Lapis K
出版信息
J Cancer Res Clin Oncol. 1982;103(1):31-8. doi: 10.1007/BF00410303.
Abstract
A new experimental model is introduced for liver metastases using intrasplenically injected Lewis lung tumor cells. The appearance of liver metastases was studied in the presence and after the removal of primary tumor. The tumorous foci in the liver proved to be natural metastases and increased in number blocking the activity of the Kupffer cells by carragheenan. This model provides a useful tool to study different aspects of liver metastases.
摘要
采用脾内注射Lewis肺癌细胞的方法，引入了一种新的肝转移实验模型。在存在原发性肿瘤和切除原发性肿瘤后，研究了肝转移的出现情况。肝脏中的肿瘤病灶被证明是自然转移灶，并且通过角叉菜胶阻断库普弗细胞的活性，其数量增加。该模型为研究肝转移的不同方面提供了一个有用的工具。
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