Artman H G, Reppert S M, Perlow M J, Swaminathan S, Oddie T H, Fisher D A
J Neurosci. 1982 May;2(5):598-603. doi: 10.1523/JNEUROSCI.02-05-00598.1982.
The circadian characteristics of the daily rhythm in oxytocin (OT) concentrations in cerebrospinal fluid (CSF) were studied in the rhesus monkey. Monkeys subjected to constant light or constant dark for periods of 3 to 6 days manifested persistence of the CSF OT rhythm. A 12-hr phase shift in the light-dark cycle resulted in a resynchronization of the rhythm to the new lighting schedule within 3 to 4 days. Altering the daily feeding and care schedule during a period of constant darkness did not alter the expression or timing of the CSF OT rhythm significantly. These results suggest that the OT rhythm is endogenously generated and that the daily light-dark cycle normally synchronizes the rhythm to the 24-hr cycle.
在恒河猴中研究了脑脊液（CSF）中催产素（OT）浓度日节律的昼夜特征。经历3至6天持续光照或持续黑暗的猴子，其脑脊液OT节律持续存在。明暗周期的12小时相位变化导致节律在3至4天内重新同步到新的光照时间表。在持续黑暗期间改变每日喂食和护理时间表，并未显著改变脑脊液OT节律的表达或时间。这些结果表明，OT节律是内源性产生的，并且日常的明暗周期通常将节律同步到24小时周期。
