Freer J H
Toxicon. 1982;20(1):217-21. doi: 10.1016/0041-0101(82)90204-5.
Surface-active properties of alpha-toxin and delta-lysin, two cytolytic protein exotoxins of the bacterium Staphylococcus aureus are summarised. The relevance of differences in surface charge density on membranes is discussed in relation to possible mechanisms of binding and membrane penetration by alpha-toxin. An hypothesis for the mechanism of membrane disruption by delta-lysin involving the formation of hydrophilic transmembrane pores is proposed.
总结了金黄色葡萄球菌的两种细胞溶解性蛋白质外毒素α毒素和δ溶血素的表面活性特性。讨论了膜表面电荷密度差异与α毒素结合和膜穿透可能机制的相关性。提出了一种关于δ溶血素破坏膜机制的假说，该机制涉及亲水性跨膜孔的形成。
