三岁以下儿童的瑞氏综合征。
Reye's syndrome in children under three years old.
作者信息
Bellman M H, Ross E M, Miller D L
出版信息
Arch Dis Child. 1982 Apr;57(4):259-63. doi: 10.1136/adc.57.4.259.
Abstract
The National Childhood Encephalopathy Study identified 37 cases of Reye's syndrome in children aged between 2 and 36 months in a 3-year period, giving an estimated incidence in Great Britain of 0.7/100 000 children a year. The diagnostic features were neither consistently positive in these cases, nor negative in 11 others later considered not to have Reye's syndrome. The prognosis was poor; the fatality rate was 46%, and 60% of the survivors were handicapped. A surveillance scheme to investigate pathological, clinical, and epidemiological factors in this rare condition is required. This has now been set up in the UK.
摘要
全国儿童脑病研究在3年时间里确定了37例年龄在2至36个月之间的儿童患瑞氏综合征，据估计，英国每年每10万名儿童中的发病率为0.7例。这些病例的诊断特征既不始终呈阳性，在后来被认为未患瑞氏综合征的另外11例病例中也不呈阴性。预后很差；死亡率为46%，60%的幸存者有残疾。需要一个监测方案来调查这种罕见病症的病理、临床和流行病学因素。英国现已设立了这样一个方案。
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ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA. A DISEASE ENTITY IN CHILDHOOD.脑病与内脏脂肪变性。一种儿童期的疾病实体。
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